Transfusion MCQs

A patient arrived at the emergency department with melena and hematemesis. After receiving a blood transfusion, one hour later, the patient developed symptoms of shortness of breath and chest pain. A chest X-ray revealed bilateral infiltrates, and the patient was subsequently transferred to the critical care department. What might be the underlying cause of these symptoms?

Fresh-frozen plasma is to be transfused to a patient. Which of the following is not a valid indication for its use?

A patient was involved in a road traffic accident and arrived at the emergency department. During the resuscitation, it was noted that bleeding from the venipuncture site was not stopping. The patient has received 14 units of packed red blood cells (PRBCs). Laboratory results show a hemoglobin level of 11, a platelet count of 150,000, an INR of 3.4, and a PTT of 70 seconds, with normal fibrinogen levels. What would be the most suitable therapy for this patient?

A patient was diagnosed with celiac disease but has been non-compliant with dietary restrictions and now presents with anemia, with a hemoglobin level of 7.5. Additionally, the patient has IgA deficiency. A blood transfusion is needed. What type of blood product should be transfused in this case?

Various blood products were administered to a patient with aplastic anemia, and subsequently, the patient developed a high-grade fever. Suspected bacterial contamination has arisen. Among the different blood products, which one carries the highest risk of bacterial contamination?

Transfusion of a single unit of platelets is anticipated to increase the platelet count by how much?

During a blood transfusion, the patient developed a skin rash indicative of urticaria, leading to the cessation of the transfusion. Which component of the blood is most likely responsible for this type of reaction?

A patient diagnosed with aplastic anemia presents with a febrile illness and significant neutropenia. Blood transfusion is recommended. What precautions should be implemented to minimize the risk of graft-versus-host disease (GVHD)?

A patient diagnosed with acute promyelocytic leukemia (M3) was admitted for resuscitation. The CBC revealed a hemoglobin level of 11.5, a white blood cell count of 30,000, and a platelet count of 65,000. Prothrombin time (PT) was 25 seconds, activated partial thromboplastin time (aPTT) was 64 seconds, and fibrinogen level was 80. What would be the subsequent investigative step?

A patient diagnosed with thallasemia has been receiving blood transfusions since childhood, maintains a stable hemoglobin level of 10 g/L, and has a ferritin level exceeding 2500 µg/L. What is the most appropriate course of action in this case?

A patient came to the emergency department after blunt abdominal trauma. The patient is in shock with abdominal distension. Urgent transfusion was decided without cross-matching. Which one of the following can be transfused in this patient?