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Author: Farhan

Diet&Drugs

Healthy habits and practices – How to live a better life!

Healthy habits may be linked to a long lifespan. Some may talk about getting fewer diseases. For others, healthy habits may be just the looks (fat, skinny, tanned, bald, etc). Still, others may link “healthy habits” to being tall, with good muscles (for men), shiny and silky hair (for women especially), shiny teeth, a moist...

May 16, 2019 · 4 min read

cancers

Signs and symptoms of Multiple Myeloma

Multiple Myeloma is the clonal proliferation of plasma cells in the bone marrow. The signs and symptoms of multiple myeloma are very non-specific, however, skeletal-pains is among the most common presenting features. Multiple Myeloma Symptoms: Multiple Myeloma is a disease of old individuals. Thus, patients are usually more than 50 years of age. Very rarely,...

May 8, 2019 · 3 min read

students corner

Huge Hepatomegaly & Cardiomyopathy – Diagnosis?

An elderly patient was referred to Pakistan Institute of Medical Sciences OPD for the work-up of hepatomegaly and weight loss. The patient, aged 65 years, with no previous premorbid conditions, was alright 8 months back when he developed abdominal pain. The pain was diffuse, moderate in intensity, and dragging in nature. It was associated with...

May 1, 2019 · 2 min read

miscellaneous

Acute intermittent porphyria – an overview

Acute Intermittent Porphyria is an autosomal dominant disorder resulting from a partial deficiency of PBG (porphobilinogen deaminase). Acute intermittent porphyria affects the central nervous system, peripheral, somatic and autonomic nervous system. Patients may present with intermittent attacks which may be life-threatening at times. Clinical features of Acute intermittent porphyria: Acute intermittent porphyria as the name...

April 21, 2019 · 3 min read

Neurology

Duchenne Muscular dystrophy – Diagnosis & Treatment

Duchenne Muscular dystrophy is an X-linked congenital disorder where the genes are inherited from an affected parent. It is a disorder affecting primarily the skeletal muscles leading to progressive muscle weakness. Since the dystrophin gene is present on the X chromosome, it mainly affects the males. A young child with Duchenne muscular dystrophy A 13...

April 13, 2019 · 5 min read

News and updates

ARNI (Valsartan complexed with Sacubitril)- Entresto

ARNI – AR stands for Angiotensin receptor blocker and NI stands for Neprilysin Inhibitor. In patients with heart failure, the levels of atrial and brain natriuretic peptides rise when the cardiac muscles are stretched because of fluid overload. An increase in ANP and BNP levels in the blood results in a diuretic effect. Thus, these...

March 26, 2019 · 3 min read

endocrinology

Diabetes Types – What’s really new in the new classification

Diabetes is a hyperglycemic syndrome affecting almost every organ system of the body. The three diabetes types are: Type 1 Diabetes Type 2 Diabetes, and Gestational Diabetes The primary defect in diabetes is either an absolute or relative insulin deficiency or insulin resistance or both. Treatment goal of any diabetic patient is maintaining normal or...

March 20, 2019 · 4 min read

Diet&Drugs

SGLT2 inhibitors – Dapagliflozin vs Empagliflozin

Dapagliflozin and empagliflozin are the two SGLT2 inhibitors currently available in Pakistan. Worldwide, among the SGLT2 class of medicines, apart from dapagliflozin and empagliflozin, canagliflozin is also being used to treat type 2 diabetes patients. Which patients should be prescribed SGLT2 inhibitors? SGLT2 inhibitors can be used as monotherapy or in combination with metformin, insulin...

March 16, 2019 · 3 min read

Diagnose yourself

Hematuria or blood in urine – How to evaluate?

Hematuria is a common symptom affecting men and women of all ages. The cause is usually a benign one but serious underlying conditions like malignancies may manifest for the first time with hematuria. Gross versus Microscopic Hematuria: Gross hematuria is visible to the naked eye. A little as 1 ml of blood in the urine...

March 14, 2019 · 4 min read

News and updates

SJS and TEN following antibiotics use can be deadly!

A number of patients have been admitted in the medical department of PIMS with SJS and TEN (Steven Johnson Syndrome and Toxic epidermal necrolysis) following the use of antibiotics. Most of the patients developed the condition following the use of amoxicillin. One patient took a tetracycline class of the antibiotic and one developed SJS after...

March 9, 2019 · 3 min read